SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3bcb9b9d72d85dc96e6aaa3dd63641fca8b05a79cb05d3f253893a4b182b6107' 
  AND token = 'k/FqkhWIQS8a7qsRGHXFoBnD/0uzuJX4wDpYYimqRe4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}