SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c12e587bebf5b93435a9eef7a6d6a6329d036d783a0d355001c066d05604a762' 
  AND token = 'GBS4/YYzI/dZf90mdRxVZnhSXdfoQVyeQV6vs1M33Hc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}