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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a4e58da35d013194ef52e3e1b4aa03879c5c3df39c8633ebfc12321261289ab4' 
  AND token = 'Rzo3gUDzgjxil/XE4/qwaRROtlsrxowYJHks2Pix61Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}