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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fe49b6a15254facd313e4fa07614756771d52f3630e01264443c9c2862d2b5e0' 
  AND token = 'uqCqNmJgfvn0/Bxq2vamyKY31oqKqLuuXX2Nwbso2Ec=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}