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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a1c49d0d87079f1ad4c820d16c362ecdd987f8604b4f8b958d2f7335ce33b33f' 
  AND token = '3XiO4X5ZHU871DmTwFlSfCpJuOlEKFnJMoUsozXh0g8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}