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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8d639e9b39d38a399b1622f64f8afa4c057b50607f7eac6e2d02dae2ae99f39a' 
  AND token = 'sQBuIcqtFqFkWljiK0MU+SQTlKFQ5S+0xXMZjm5LanQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}