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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '51a236fb589a6d51729f7751b5154dd95b998398469caa3debb51626c6c5e764' 
  AND token = '0FoHbHayj6n+txTLTvo8N7y883ZbNwmYm0iypS68hMU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}