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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ca860bf48e7e0aea50915ebd33c9774da522e521b112113af299af407144b832' 
  AND token = 'CqXJy5ccxkncWZXm2PfyNnW0ZwzAi00FZx9YM1KREbk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}