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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '95395628d6cca0bdef158fb6c949e37c5cd988c3933a2c26f27aa5cf10910c2d' 
  AND token = '+gDaU/a8xWBBRcAkQmlx36nkanNiMoiiMQKvZkVFQVQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}