SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4693b8e20c2e98157a7b5799b38cfca3c460d0b8b45ea3f31d075f63c82806a5' 
  AND token = 'AVFtYIOxMniW7cKuPCKCgaEYQFGJsXLwz8raI46zd2M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}