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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a546ae22abbccad5314ebcc3356850ea98205a21c930e0cd2fb14901dbc0c372' 
  AND token = 'QKR8MXOW+pt77uQLa3JD91wc8u/Kur7k3d32m6zqUQI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}