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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45d33cc433dda310584a4841721cfc271cd1ca4287253003335ec08a6cf4cd9b' 
  AND token = '17Ctv+Kvgv+Xueh4kNcvgkPDDdAztAQZRbsMtDMDcqw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}