SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2c832546e796d1b70a7fbc929ba844922cc47f0a1b5b9733b88fcb4b9b91a56f' 
  AND token = 'Vl3GEXZQ4xVc987djUbc/p8tnQANXZCqxr0NX2QWyl0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}