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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e999484845252e67c9367e42cbb61b8a2ba50668118d8b09974f682ca8f1c71' 
  AND token = 'SzkIIFHCi3P+ZU9g5zWrWyP2iPfhHZcLDJ0yn+llNLQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}