SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2718db403b5f2d92ae79f18c3006a7dab83ecb8ed7cb97511ca0418abaeb01b6' 
  AND token = 'EZcL+ybN3/Y8rmh2RBk9HaCHfapGpn0itvAymp3C5RA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}