SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8033364bd86c44bae3ae454526d0e142cd96821ed93d7f95407db9de5b15ee18' 
  AND token = 'CsBzc4YBW5qcGY3sSaqfY/zytATsxCF7KbUHU9z8DRo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}