SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd72b6c1184b4b489131f3807f98f228e3df28afa5c6c9d42d7e80202050d51e7' 
  AND token = 'XSv8vOiylM4LHClAGGmDudessHftUnbOiF23TdnqQQE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}