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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1570e2384160662ad02f4cbcdb9ff64c5562024a520376a432a48d27297e332e' 
  AND token = '1lygLAoi/BQKLN+ukXc6M9yeWD7t3poIgaMb4f4kjYM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}