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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '70ccdd0f17d34639efecf51c456a981f8c7099faa0d68a4428c6e872776ef578' 
  AND token = 'UWtcV+GjpIXrVpPYgnfPWgCeUx+1GjzioLoo35N5Mnw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}