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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5b5ecef23e5970f73be4ab5ae6321ca75e643a0d00868e39845590cdef59825d' 
  AND token = 'Ialf7rt4tiuM+q4g+ogwhe9uPEhLIVJgmeiZFQLP/eY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}