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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f1b49001cd37a948080ddff315aefa2ca7864a3861a9ed0c54f603dfb441ee0f' 
  AND token = 'FNv5S+JiEgPxay/4czHAS1YVyI4iBehZWBpuvNptA5k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}