SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '642e57d0d6a907f5803373964a1129bf778b6a737a56d2603dd1a6022e5b9d76' 
  AND token = 'I26kPukCof5wgLIWNOkUXBLrf2yiKWCEuo4ZnqdBaDM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}