SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9990ade292012336ce863f9254701226162d5a2be6ba9ab52198d6aca207f1a1' 
  AND token = 'VLiUiuOHQow/m7bQCzXcnA4CzDd+JUsg7WOnWNPqaW8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}