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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cb7fe82488d06e794c462a0fa1c60f9da17604b66c53c4a0d6c3130302e94649' 
  AND token = 'WkMsm2DGKOtIFhBopJ+MpFXUb+Ae2Ev4hcIAMS5qOxg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}