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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd040442f294b2f08b22433f3904ef166d513a7e0b85ed882ca3d185f48e956e9' 
  AND token = 'Gi5VygW201PwDwdfrUNTiCSDaS78ZCdKexHD45L0E40=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}