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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0d76de58caf33e81eef5f116f0f143b320122327a0eb010b5d2870972f4c35aa' 
  AND token = 'dG6Yas1+pOWyiyT23DE+n9sPjIbkXgKtAZfCt5zMStU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}