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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '09c7852edac31d8c85283b7d921b9845709fe484d2c530a495d741226999a93f' 
  AND token = '8qXyFpkVPUX2lUrrtf/2WJVhH8u2zcmxZx+6FObyYfI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}