SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6ad82d85e79a123fb359ebcd41e7b9e9beb015d62775c6cfeb486fe63203a16b' 
  AND token = 'Z7H/KGCv/1SLf4OvN6AVCFRgE+6y2nvn131rZx2A5PM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}