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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22a8634eb129d1d08d43c7eb95c92a923443a1abc23a0d47fbfc4c158b179a81' 
  AND token = 'pfOkFUmIu65Ylimp63gjSPk+Dpn4UQGEnDI+clUfKq0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}