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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a579b2b63a97007d0a20d26d10a11f0fbff43dfeab1f9dbbd510faee80ae767e' 
  AND token = 'POGY+cqpd86kjtr87NBH9p8RBr611LaMTNsCjx5Frus=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}