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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '602ad5f90dd649e485b5dff74b2cb151be59716dd1e3a44e91752d8a624f70b6' 
  AND token = 'VF7qdvBX5akgF7NSY2g49oFyWI4DlohBV329tLsejYE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}