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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8b906634c3b3667b654d4f7c735698d62da827d84adc161e497a75ec0df6f2dd' 
  AND token = 'ULCd9CfUuBY5hAzUAdHc/D/A/PPEZd+o9ZzSG0Ux3kA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}