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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '661c55a46a620c705f8ee2ae61ee5605457cfaf1111137d8d3210b17d4f832bc' 
  AND token = 'eEwP354w83u7wn/uf0+cnU2qrBkDVw2YjDLkJ91nGX4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}