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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7695c154397353736a7f64b108ef5ca10f2baa286513e8e2441379514b0b1eea' 
  AND token = 'XpR+S3B7qJF6rM0nhJe2AhcW0chyitpOsxO9VOBo4d4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}