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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1a45c6fa21c318c1f67fb50a50f31786c44b8eef9b6a4ab1540caa05fb84c700' 
  AND token = 'FiangZMb/IJ1F9j437SP2rDbHJNIDIToV0COHLNwZps=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}