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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e122a1d292c0dc0d706e12ebffff686ec32849dbd14b1cacfc118a006d0aff4c' 
  AND token = 'Ho51SPbSAuYaxsvNUCzm60B+DQ5A1mE4r7OoFRJ3Kbo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}