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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65b2982ac5b9f1cb2a28795230b30135486e9de81495c231465ce99021cba15a' 
  AND token = 'UOLJdUIQtP8wlnl/3ejcjIa6WVS7CawxqRufgxkDTzg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}