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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2df35d292e8596f23cfa9189cf3f432dae17a781969b021a45166f0b3d5f926d' 
  AND token = '6CuMM85WS/M96zRtTL8y+WCXiNMXG6XUWlY6c2LwGJ4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}