SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80574d951df3959bd534d1624a452fc12878318905b5e1a9988c760b000635e1' 
  AND token = 'TH0Mt75GTL1hNjpjw0OABNfTJVINRCSAuCAHHAd5M2k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}