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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5b96c6a51f332bb1a2ffe06df110b3ddcc2faabdf9412c6eb312bddd01e05225' 
  AND token = 'pPfKZzmABr69r53GCo/6lJBG1/3GHfXpq1+A4j4N9Qc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00058

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}