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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f6dfb266f9e8002f4f98d9e38cabdf07ca4e1cb4c81b08dfb23d996a135ae1da' 
  AND token = 'S5hPTVTAuLJy7cnmLKmdEwhdJeB1+twJm+SinNCt3MY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}