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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ca997bb20e5591d0284056145e899e0ac322d2198f744798239c38e4c97544f0' 
  AND token = 'orpAvwGuqdEOYlY8NqoCCDuyG7jP2gICqRil422I8Ro=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}