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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4ec7485d3c2c3c6a8a5b9d69a9a549832f950706d7f50c18ab20d69970c3b538' 
  AND token = 'vuCfd5AGe037ySPdQ8inCWJJxOU8Ztqb8E0A32WYiVE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}