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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c2cda2bb0cbfaa81c1542b66155ebdacd895f840b98ac43312678dda6210a512' 
  AND token = 'm2cl5GPLxe4AzEiDUn+2IUQ1mv9MUMSUKEWK2sj0vpw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}