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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2fe450e4a7308880e25ad5e284b65b0b0d72d016590acb4235c3b6358fdcd846' 
  AND token = 'YyOWNinBDqz+djYDL4sKHpW6EPNjl+kztwn+RNHyCvE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}