SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1be339b69bc0e52d8fb07bbec041a3cc5194e80da844520c75d690dafafe2c98' 
  AND token = 'pj6N8Dc2pPuOIQLhlKgtLZKoW4nJV8jevewZ1P5Vzxo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}