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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3607c346f52c7fea8d555fb7580c1e70ba7537184752db1f26622e9a930a0a68' 
  AND token = '7f4Bhk1v43iI47bxcdeids366SbzeN8RcpCS/BauElY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}