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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4c9567df58d9813043944da1a13f144ee3f2452aea1907d4f2d852eaea10ef18' 
  AND token = 'vH7zSybGaMnqfIt91kBAb+ku+otxJWTZ0gqOETan6qA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}