SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '137aedf65f9eb2a1b63f479fb496557e02599dfc1f8b64f5dd267680068fc703' 
  AND token = 'VeU6/37QGuXD2v9sHMi+DEkuNaVTnHzXOw3p1icebSU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}