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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '395121ee7197d3fb448f42381c58c7b5d23a8c048e00863789fe454c7e57bb0e' 
  AND token = 'aT5oZZ77AlfbDVZz6oAGTyIdSC1KxVz18FRNWSXFJjg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}